Department of Experimental Biology

Articles

• Assembly of the Xrn2/Rat1–Rai1–Rtt103 termination complexes in mesophilic and thermophilic organisms

  DIKUNOVÁ Alžbeta NOSKOVÁ Nikola OVERBECK Jan H. POLÁK Martin STELZIG David ZAPLETAL David KUBÍČEK Karel NOVÁČEK Jiří SPRANGERS Remco ŠTEFL Richard

  Article in Periodical

  Structure, year: 2025, volume: 33, edition: 2, DOI

• Automated Engineering Protein Dynamics via Loop Grafting: Improving <i>Renilla</i> Luciferase Catalysis

  PLANAS IGLESIAS Joan MAJEROVÁ Marika PLUSKAL Daniel VAŠINA Michal DAMBORSKÝ Jiří PROKOP Zbyněk MAREK Martin BEDNÁŘ David

  Article in Periodical

  ACS Catalysis, year: 2025, volume: 15, edition: 4, DOI

• Bioconjugates of photon-upconversion nanoparticles with antibodies for the detection of prostate-specific antigen and p53 in heterogeneous and homogeneous immunoassays

  MAKHNEVA Ekaterina ŠPAČEK Pavel HLAVÁČEK Antonín WEISOVÁ Julie GORRIS Hans-Heiner SKLÁDAL Petr FARKA Zdeněk

  Article in Periodical

  Nanoscale, year: 2025, volume: 17, edition: 18, DOI

• Biochemical and Computational Characterization of Haloalkane Dehalogenase Variants Designed by Generative AI: Accelerating the SN2 Step

  GELFAND Natalia OREL Vojtěch CUI Wenqiang DAMBORSKÝ Jiří LI Chenglong PROKOP Zbyněk XIE Wen Jun WARSHEL Arieh

  Article in Periodical

  Journal of the American Chemical Society, year: 2025, volume: 147, edition: 3, DOI

• BRCA1 and BRCA2 as prognostic markers in oral squamous cell carcinoma: a minireview

  GEDEONOVA Dominika BIANCHI Claretta STEMBIREK Jan HRDINKA Matous CHYRA Zuzana BUCHTOVÁ Marcela HURNIK Pavel BLAZEK Tomas REZNAROVA Jana

  Article in Periodical

  Frontiers in Oncology, year: 2025, volume: 15, edition: March, DOI

• Breaking boundaries: role of the brain barriers in metastatic process

  NASIM Izadi MARYAM Shahidian Akbar SOLÁR Peter KLARA Mrazova HAŠANOVÁ Klaudia MARTIN Bartosik ZAMANI Alemeh TOMAS Kazda SHAHIDIAN AKBAR Maryam ROMAN Hrstka MRÁZOVÁ Klára JOUKAL Marek BARTOŠÍK Martin KAZDA Tomáš HRSTKA Roman JOUKAL Marek

  Article in Periodical

  FLUIDS AND BARRIERS OF THE CNS, year: 2025, volume: 22, edition: 1, DOI

• Brucella microti and Rodent-Borne Brucellosis: A Neglected Public Health Threat

  RUDOLF Ivo KEJÍKOVÁ Romana KOSOY Michael HUBÁLEK Zdeněk MRAVCOVÁ Kristína ŠIKUTOVÁ Silvie WHATMORE Adrian M SASCHA Al Dahouk

  Article in Periodical

  Zoonoses and Public Health, year: 2025, volume: 72, edition: 1, DOI

• Cancer stem cells: Masters of all traits

  LECK Lionel Y. W. EL-AZIZ Yomna S. Abd MCKELVEY Kelly J. PARK Kyung Chan SAHNI Sumit LANE Darius J. R. ŠKODA Jan JANSSON Patric J.

  Article in Periodical

  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, year: 2025, volume: 1871, edition: 3, DOI

• Depleting chemoresponsive mitochondrial fission mediator DRP1 does not mitigate sarcoma resistance

  BOŘÁNKOVÁ Karolína SOLNÝ Matyáš KRCHNIAKOVÁ Mária ŠKODA Jan

  Article in Periodical

  Life Science Alliance, year: 2025, volume: 8, edition: 2, DOI

• Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε

  HAAG Adrian NEMEC Vaclav JANOVSKÁ Pavlína BARTOŠÍKOVÁ Jana ADHIKARI Bikash MUELLER Juliane SCHWALM Martin P ČADA Štěpán OHMAYER Uli DAUB Henrik KIM Yeojin BORN Florian WOLF Elmar BRYJA Vítězslav KNAPP Stefan

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2025, volume: 68, edition: 1, DOI